Un aperçu des capacités et des projets de recherche du Centre national de référence pour les essais biologiques et la surveillance in vivo

The National Calibration Reference Center (NCRC) for Bioassay and In Vivo Monitoring was established in 1982 within Health Canada’s Radiation Protection Bureau. It improves workplace safety through testing that measures workers’ internal exposures to radiation.

NCRC provides performance testing programs for in vivo and in vitro bioassay. Clients include universities, hospitals, public utilities, and private firms. Their performance tests align with specifications of the Canadian Nuclear Safety Commission Regulatory Document, REGDOC-2.7.2, Dosimetry, Volume II: Technical and Management System Requirements for Dosimetry Services. NCRC is ISO 9001 registered.

Programs

Currently, NCRC provides eight bioassay performance testing programs on an annual basis.

In vitro programs: Tritium Carbon-14 Dual tritium and carbon-14 Fission and activation products Uranium

In vivo programs: Whole-body counting Lung counting Thyroid counting (I-123,I-125, I-131)

For more information, see the Programs and Services section of the NCRC webpage.

Research in bioassay measurements

NCRC also participates in research projects on the accuracy of bioassay measurements. Topics include

• determination of factors that influence results,
• phantom design and fabrication, and
• methodology improvements.

We also collaborate with other national or international organizations such as the the European Radiation Dosimetry Group (EURADOS) and PROCORAD (an international network that provides its members with annual inter-laboratory comparisons).

In addition, the centre can provide individual monitoring using in vivo and in vitro bioassay measurements of people who may have been contaminated with radionuclides.

NCRC is using techniques including MCNP (Monte Carlo N-Particle) simulations to develop or improve measurement.

Latest developments

The latest innovation is using 3D printing technology to produce new, in-house anthropomorphic phantoms. For example, this technology was used to redesign the NCRC thyroid and lung phantoms for our performance test programs.

3D printed neck, thyroid inserts, and lung sets